Olafs Daugulis

Olafs Daugulis
Associate Professor
	Office: 168 Fleming Phone: (713) 743-9381 Email: olafs@uh.edu Education Riga Technical University, Riga, Latvia 1991 PhD, University of Wisconsin-Madison 1999 Postdoctoral Associate, University of North Carolina at Chapel Hill 2000-2003 Honors, Fellowships, etc. S.C. Slifkin Scholarship, University of Wisconsin-Madison, 1996 Synthesis-Synlett Journal Award, 2005 NSF Career Award, 2007, declined due to overlap with NIH funding A. P. Sloan Fellowship 2008 Camille Dreyfus Teacher-Scholar Award 2008 UH Excellence in Research and Scholarship Award at Assistant Prof. level 2009 Chem 3331 - Honors Organic Chemistry Info
One undergraduate research position available. Requirements: must be a chemistry major, must have passed Chem 3331 and Chem 3332 with a grade B or higher at UH. Must be willing to consider chemistry graduate school. Please contact Dr. Daugulis by email if interested.
There are no jobs for Computer Science students or any other students who are not registered at the Department of Chemistry. Such requests will be treated as spam and reported.

Research Interests

Broad interests in synthetic organic and organometallic methodology including:
• Group 11 metal chemistry
• Application of organometallic chemistry to organic synthesis and polymer chemistry
• Development of new enantio- and diastereoselective transformations
Students and postdocs in our group will be exposed to research at the convergence of organic, organometallic and polymer chemistry, often having direct technological applications. The training will provide these individuals with the capacity to make contributions in both science and technology.

Recent Publications

"Catalytic Coupling of Haloolefins with Anilides" Zaitsev, V. G.; Daugulis, O. J. Am. Chem. Soc., 2005, 127, 4156.

"Anilide ortho-Arylation Using C-H Activation Methodology" Daugulis, O.; Zaitsev, V. G. Angew. Chem. Int. Ed., 2005, 44, 4046.

"Catalytic Coupling of C-H and C-I Bonds Using Pyridine As a Directing Group" Shabashov, D.; Daugulis, O. Org. Lett., 2005, 7, 3657.

"Highly Regioselective Arylation of sp³ C-H Bonds Catalyzed by Palladium Acetate" Zaitsev, V. G.; Shabashov, D.; Daugulis, O. J. Am. Chem. Soc., 2005, 127, 13154.

"Monomeric Ag(I) ß-Diketiminate Complexes" Chiong, H. A.; Daugulis, O. Organometallics, 2006, 25, 4054.

"Regioselective Functionalization of Unreactive C-H Bonds" Daugulis, O.; Zaitsev, V. G.; Shabashov, D.; Pham, Q.-N.; Lazareva, A. Synlett, 2006, 15, 3382.

"ortho-Arylation of Benzamides" Shabashov, D.; Daugulis, O. Org. Lett., 2006, 8, 4947.

"Direct Palladium-Catalyzed ortho-Arylation of Benzylamines" Lazareva, A.; Daugulis, O. Org. Lett., 2006, 8, 5211.

"Palladium-Catalyzed Arylation of Electron-Rich Heterocycles with Aryl Chlorides" Chiong, H. A,; Daugulis, O. Org. Lett., 2007, 9, 1449.

"Two Methods for Direct ortho-Arylation of Benzoic Acids" Chiong, H. A.; Pham, Q.-N.; Daugulis, O. J. Am. Chem. Soc., 2007, 129, 9879.

"Palladium-Catalyzed Anilide ortho-Arylation and Subsequent One-Pot Cyclization to Phenanthridines" Shabashov, D.; Daugulis, O. J. Org. Chem., 2007, 72, 7720.

"Copper-Catalyzed Arylation of Heterocycle C-H Bonds" Do, H.-Q.; Daugulis, O.* J. Am. Chem. Soc., 2007, 129, 12404.

"Copper-Catalyzed Arylation and Alkenylation of Polyfluoroarene C-H Bonds" Do, H.-Q.; Daugulis, O. J. Am. Chem. Soc., 2008, 130, 1128.

"Carbon-Hydrogen Bond Functionalization Approach for the Synthesis of Fluorenones and ortho-Arylated Benzonitriles" Shabashov, D.; Maldonado, J. R. M.; Daugulis, O.* J. Org. Chem., 2008, 73, 7818.

"Direct Transition-Metal-Free Intramolecular Arylation of Phenols" Bajracharya, G.; Daugulis, O. Org. Lett., 2008, 10, 4625.

"A General Method for Copper-Catalyzed Arylation of Arene C-H Bonds" Do, H.-Q.; Khan, R. K. M.; Daugulis, O. O. J. Am. Chem. Soc. 2008, 130, 15185.

"A Simple Base-Mediated Halogenation of Acidic sp² C-H Bonds under Noncryogenic Conditions" Do, H.-Q.; Daugulis, O. Org. Lett. 2009, 11, 421.

"Palladium (II) Acetate-Butyldi-1-Adamantyphosphine Catalyzed Arylation of Electron-Rich Heterocycles. Preparation of 5-Phenyl-2-Isobutylthiazole" Lazareva, A.; Chiong, H. A.; Daugulis, O. Org. Synth. 2009, 86, 105.

"Palladium- and Copper-Catalyzed Arylation of Carbon-Hydrogen Bonds" Daugulis, O.; Do, H.-Q.; Shabashov, D. Acc. Chem. Res. 2009, 42, 1074.

"Palladium and Copper Catalysis in Regioselective, Intermolecular Coupling of C-H and C-X Bonds" Daugulis, O. Topics in Current Chemistry, in press. Invited review.

"Copper-Catalyzed Arene C-H Bond Cross-Coupling" Do, H.-Q.; Daugulis, O. Chem. Commun., in press.

"Direct Conversion of Carbon-Hydrogen to Carbon-Carbon Bonds by First Row Transition Metal Catalysis" Kulkarni, A. A.; Daugulis, O. Synthesis, in press.

"In Situ Generation and Trapping of Aryllithium and Arylpotassium Species by Halogen, Sulfur, and Carbon Electrophiles" Popov, I.; Do, H.-Q.; Daugulis, O. J. Org. Chem., ASAP article.